Key Publications

Frizzled7 antibody-functionalized nanoshells enable multivalent binding for Wnt signaling inhibition in triple negative breast cancer cells Riley RS, Day ES.. Small. 2017; 13(26): 1700544.

Antibody-nanoparticle conjugates to improve the sensitivity of ELISA-based detection methods Billingsley MM, Riley RS, Day ES.. PLOS ONE. 2017; 12(5); e0177592.

Nanoshell-mediated photothermal therapy can enhance chemotherapy in inflammatory breast cancer cells Fay BL, Melamed JR, Day ES.. International Journal of Nanomedicine. 2015; 10: 6931-6941.

Your Patient Got a Dense Breast Notifi cation with Her Mammogram Report: What Are You Supposed to Do? Dickson-Witmer, D. Sabesan, A. Del Med J .March 2018, 90(3) 76-81.

ACS CRP Dissemination and Implementation Committee issues call for participants in pilot project. Dickson-Witmer D, Blair S, Boughey JC. Bull Am Coll Surg. 2017 Jun;102(6):48-50. PMID: 28885810.

Dense Breasts: What Do Our Patients Need to Be Told and Why?Throckmorton AD, Rhodes DJ, Hughes KS,, Degnim AC, Dickson-Witmer D, Ann Surg Oncol. 2016 Oct;23(10):3119-27PMID: 27401446.

Dissemination and implementation: Translating cancer guidelines and clinical trial outcomes into everyday practice. Wilke LG, Dickson-Witmer D, Boughey JC. Bull Am Coll Surg. 2016 Feb;101(2):33-4. No abstract available.PMID: 26995861.

Performance and Practice Guideline for the Use of Neoadjuvant Systemic Therapy in the Management of Breast Cancer.Holmes D, Colfry A, Czerniecki B, Dickson-Witmer D, Francisco Espinel C, Feldman E, Gallagher K, Greenup R, Herrmann V, Kuerer H, Malik M, Manahan E, O’Neill J, Patel M, Sebastian M, Wheeler A, Kass R.Ann Surg Oncol. 2015 Oct;22(10):3184-90. doi: 10.1245/s10434-015-4753-3. Epub 2015 Jul 30. Review. PMID: 26224406.

Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group. Provenzano E, Bossuyt V, Viale G, Cameron D, Badve S, Denkert C, MacGrogan G, Penault-Llorca F, Boughey J, Curigliano G, Dixon JM, Esserman L, astner G, Kuehn T, Peintinger F, von Minckwitz G, White J, Yang W, Symmans WF, Dickson-Witmer, D; Residual Disease Characterization Working Group of the Breast International Group-North American Breast Cancer Group Collaboration. Mod Pathol. 2015 Sep;28(9):1185-201. doi: 10.1038/modpathol.2015.74. Epub 2015 Jul 24.PMID: 26205180.

Clinical Performance of Synthesized Two-dimensional Mammography Combined with Tomosynthesis in a Large Screening Population. Aujero, M., Holt, JS. Radiology. April 2017,283(1) 70-76.

Fabrication of Complex Functional Biomaterial Microstructures by In situ Photopolymerization and Photodegradation,PJ LeValley, B Noren, PM Kharkar, AM Kloxin, JC Gatlin, J Oakey, ACS Biomaterials Science & Engineering, In Press. DOI: 10.1021/acsbiomaterials.8b00350.

Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications, PJ LeValley, EO Ovadia, CA Bresette, LA Sawicki, E Maverakis, S Bai, AM Kloxin, “ Chemical Communications, 54, 6923-6926, 2018. DOI: 10.1039/C8CC03218A.

Design of Synthetic Extracellular Matrices for Probing Breast Cancer Cell Growth Using Robust Cyctocompatible Nucleophilic Thiol-yne Addition Chemistry LJ Macdougall, KL Wiley, AM Kloxin, AP Dove, Biomaterials, 178, 435-447, 2018. DOI: 10.1016/j.biomaterials.2018.04.046.

Designing photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells. EO Ovadia, DW Colby, AM Kloxin, Biomaterials Science, 6, 1358-1370, 2018. DOI: 10.1039/c8bm00099a.

Fast, Irreversible Modification of Cysteines through Strain Releasing Conjugate Additions of Cyclopropenyl Ketones NJ Smith, K Rohlfing, LA Sawicki, PM Kharkar, SJ Boyd, AM Kloxin, JM Fox, Organic & Biomolecular Chemistry, 16, 2164-2169, 2018. DOI: 10.1039/C8OB00166A.

Techniques for the isolation and identification of proteins secreted by cells cultured within synthetic extracellular matrices LA Sawicki, LH Choe, KL Wiley, KH Lee, AM Kloxin, ACS Biomaterials Science and Engineering, 4, 836-845, 2018, 2018.  DOI: 1021/acsbiomaterials.7b00647.

Image-Guided, Laser-Based Fabrication of Vascular-Derived Microfluidic Networks.” Journal of Visualized Experiments . K.A. Heintz, D. Mayerich, & J.H. Slater. “. 2017. [JoVE Video].

Fabrication of 3D Biomimetic Microfluidic Networks in Hydrogels K.A. Heintz, M.E. Bregenzer, J.L. Niemczyk, K.H. Lee, J.L. West, & J.H. Slater. Advanced Healthcare Materials. 2017.

A Strategy Toward Icetexane Natural Products Moon, DJ; Al-Amin, M;. Lewis, RS. ; Arnold, KM; Glenn P. Yap, A.; Sims-Mourtada, J; Chain, WJ;. – Eur. J. Org. Chem. 0.1002/ejoc.20180070.

The impact of radiation on the tumor microenvironment: effect of dose and fractionation schedules. Arnold, KM, Flynn, NJ, Raben, A, Romak, L, Yu, Y, Dicker, AP, Mourtada, F, Sims-Mourtada, J. 2018 Mar 9;11:1179064418761639. doi: 10.1177/1179064418761639. eCollection 2018. Review.

Co-activation of Hedgehog and WNT signaling pathways is associated with poor outcomes in triple negative breast cancer. Arnold, KM, Pohlig, RT., Sims-Mourtada, J. Oncology Letters 14, 5285-5292. https://doi.org/10.3892/ol.2017.6874.

The Multifaceted Roles of B Cells in Solid Tumors: Emerging Treatment Opportunities. Flynn, NJ., Somasundrum, R., Arnold, KM., Sims-Mourtada, J.. Target Oncol. 2017 Mar 9. doi: 10.1007/s11523-017-0481-x. PMID: 28281220.

Obesity in breast cancer: Do age, race and subtype matter? Arnold, K.M., Flynn, N.J., Sims-Mourtada, J. Cancer Res Ther 2016, 2( 5) :021.

Activation of Inflammatory Responses Correlate With Hedgehog Activation and Precede Expansion of Cancer Stem-Like Cells in an Animal Model of Residual Triple Negative Breast Cancer after Neoadjuvant Chemotherapy.Arnold, K.M, Flynn, N. J, Sims-Mourtada, J. Cancer Studies and Molecular Medicine. 12/2015; 2(2):80-86. PMID: 25674014.