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Clinical Trials

Types of Drug Clinical Trials

Medical research studies are categorized in four phases.

 Medical Research Phases

On average, it takes 15 years before a drug tested in the laboratory can be tested on humans. Only five in every 5,000 compounds tested in the lab ever make it to human testing. Only one in five of those are approved for sale in the United States.

After initial laboratory and animal studies, medicines that are tested in people must follow rigid guidelines set by the U.S. Food and Drug Administration (FDA).

Medical research studies are categorized in four phases:

  • Phase I clinical trials involve healthy volunteers. These trials are designed to test a drug’s safety and to determine how it works in the human body.
  • Phase II studies test the effectiveness of the drug on a few hundred volunteer patients who have the disease the drug is designed to treat.
  • Phase III trials involve several thousand volunteer patients who are closely monitored in clinics and hospitals to confirm the effectiveness of the drug in treating their illness and to identify any adverse effects.
  • Phase IV trials are sometimes required by the FDA to evaluate any long-term effects of a drug or treatment.

Useful Links

Doctor explaining trials to female patient
OB/GYN Clinical Trials
The purpose of this research study is to find out whether pessary or vaginal progesterone lowers the risk of babies being born preterm to women.
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ChristianaCare Study Points to Potential New Drug Combination Strategy for Colorectal Cancer
ChristianaCare Study Points to Potential New Drug Combination Strategy for Colorectal Cancer
Grant from Delaware Bioscience Center for Advanced Technology will help move the research toward an early-stage clinical study
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