Research at ChristianaCare

At ChristianaCare, research is a key element to providing quality health care in every medical specialty. It helps us to create innovative, affordable systems of care that our neighbors value.

There are hundreds of multicenter national, regional and locally based studies in progress led by ChristianaCare investigators on our hospital campuses and other patient care facilities, as well as at affiliates throughout the region. Many research trials are open for enrollment. Your help is critical to their success.

ChristianaCare’s Gene Editing Institute, a worldwide leader in CRISPR gene editing technology and the only institute of its kind based within a community health care system in the United States, takes a patient-first approach in its research to improve the lives of people with life-threatening disease. Since 2015, its researchers have been involved in several ground-breaking firsts in the field, including the development of the first CRISPR gene editing tool to allow DNA repairs outside the human cell which will rapidly speed therapies to patients and a unique version of CRISPR called EXACT that reduces the number of off-target edits to other areas of the genome, which is vital for further research and patient applications. Researchers are currently developing a patient trial for lung cancer using CRISPR and employing the technology to combat the COVID-19 pandemic.